2-Chlorobenzylamine → HCID 9888570, compound

HRID 852175Notes

Reaction equation

HRID 852175 reaction equation
[S:1]1[CH:5]=[C:4]([C:6]2[CH:16]=[CH:15][C:9]([O:10][CH2:11][CH:12]3[CH2:14][O:13]3)=[CH:8][CH:7]=2)[C:3]2[CH:17]=[CH:18][CH:19]=[CH:20][C:2]1=2.[Cl:21][C:22]1[CH:29]=[CH:28][CH:27]=[CH:26][C:23]=1[CH2:24][NH2:25]>C(O)C>[S:1]1[CH:5]=[C:4]([C:6]2[CH:16]=[CH:15][C:9]([O:10][CH2:11][C@H:12]([OH:13])[CH2:14][NH:25][CH2:24][C:23]3[CH:26]=[CH:27][CH:28]=[CH:29][C:22]=3[Cl:21])=[CH:8][CH:7]=2)[C:3]2[CH:17]=[CH:18][CH:19]=[CH:20][C:2]1=2

Participants

4

Reactant 2

HCID 666482-ChlorobenzylamineHCID 17906295HCID 17906295, compound

Product 1

HCID 9888570HCID 9888570, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The title compound is prepared from a mixture of 2-(4-benzo[b]thiophen-3-yl-phenoxymethyl)-oxirane, 2-chlorobenzylamine and ethanol essentially as described above in Example 94. Purity by LC/MS=99%, [M+H]+=424.

Sources & evidence

ORD record
ord-92f1d298cf8e44ed92948488fcb5e5f9
Source dataset
uspto-grants-2007_08
Patent number
US07253165B2

Reaction notes

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