(+-)-1-Aminoindan → HCID 58928266, compound

HRID 852180Notes

Reaction equation

HRID 852180 reaction equation
[S:1]1[CH:5]=[C:4]([C:6]2[CH:16]=[CH:15][C:9]([O:10][CH2:11][CH:12]3[CH2:14][O:13]3)=[CH:8][CH:7]=2)[C:3]2[CH:17]=[CH:18][CH:19]=[CH:20][C:2]1=2.[NH2:21][CH:22]1[C:30]2[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=2)[CH2:24][CH2:23]1>C(O)C>[S:1]1[CH:5]=[C:4]([C:6]2[CH:16]=[CH:15][C:9]([O:10][CH2:11][C@H:12]([OH:13])[CH2:14][NH:21][CH:22]3[C:30]4[C:25](=[CH:26][CH:27]=[CH:28][CH:29]=4)[CH2:24][CH2:23]3)=[CH:8][CH:7]=2)[C:3]2[CH:17]=[CH:18][CH:19]=[CH:20][C:2]1=2

Participants

4

Reactant 2

HCID 123445(+-)-1-AminoindanHCID 17906295HCID 17906295, compound

Product 1

HCID 58928266HCID 58928266, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The title compound is prepared from a mixture of 2-(4-benzo[b]thiophen-3-yl-phenoxymethyl)-oxirane, 1-aminoindane and ethanol essentially as described above in Example 96. Purity by LC/MS=100%, [M+H]+=416.

Sources & evidence

ORD record
ord-b1d38db880a0485b969d2a29f8984c98
Source dataset
uspto-grants-2007_08
Patent number
US07253165B2

Reaction notes

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