Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetonitrile → HCID 9842821, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetonitrile | HCID 6342 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-Thiophenemethylamine | HCID 2776381 | — |
| 반응물 | HCID 17906314 | HCID 17906314 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | HCID 9842821 | HCID 9842821 | — |
반응 단계
The title compound is prepared from 3-[4-(3-bromo-propoxy)-phenyl]-benzo[b]thiophene, C-thiophene-3-yl-methylamine (Table No. 1, SM 9), potassium carbonate and acetonitrile essentially as described above in Example 118 except that the column chromatography is performed with a graded solvent mixture from 100% ethyl acetate to 10% methanol in ethyl acetate. Purity by LC/MS=99%, [M+H]+=380.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07253165B2 |
| 출처 데이터셋 | uspto-grants-2007_08 |
| ORD ID | ord-b433855337014105ba8d5758ac46d643 |
| 출처 메모 | uspto-grants-2007_08 |