HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 58928260, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-[4-(3-Bromo-propoxy)-phenyl]-benzo[b]thiophene | HCID 17906314 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 58928260 | HCID 58928260 | — |
Reaction Steps
The title compound is prepared from 3-[4-(3-bromo-propoxy)-phenyl]-benzo[b]thiophene, hexamethyleneimine, potassium carbonate and acetonitrile essentially as described above in Example 118 except that the column chromatography is performed with a graded solvent mixture from 100% ethyl acetate to 10% methanol in ethyl acetate. Purity by LC/MS=100%, [M+H]+=366.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07253165B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-623e50217a0a4349b15b05fa9535f253 |
| Source note | uspto-grants-2007_08 |