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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 852230Generated: October 30, 2026

Thiophene-3-boronic acid → HCID 22038553, compound

https://huagongshe.com/reaction/852230

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiophene-3-boronic acidHCID 581760—
ReactantHCID 22038560HCID 22038560—
ProductHCID 22038553HCID 2203855375.3%

Reaction Steps

8-Bromo-3-(2-methyl-2-nitropropyl)imidazo[1,2-a]pyridine (1.0 g, 3.35 mmol) and thiophene-3-boronic acid (0.64 g, 5.0 mmol) are coupled as described in Amine 14 to give 760 mg of 3-(2-methyl-2-nitropropyl)-8-(3-thienyl)imidazo[1,2-a]pyridine (75%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07253181B2
Source datasetuspto-grants-2007_08
ORD IDord-92e2bfbb6f174d2eb09cb96b72aab214
Source noteuspto-grants-2007_08