HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Trifluoromethyl)aniline → 2-[2-(3-trifluoromethylphenyl)-2H-tetrazol-5-yl]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Trifluoromethyl)aniline | HCID 7375 | — |
| Reactant | 2-Pyridinecarboxaldehyde | HCID 14273 | — |
| Reactant | 2-[2-(3-chlorophenyl)-2H-tetrazol-5-yl]pyridine | HCID 9921369 | — |
| Product | 2-[2-(3-trifluoromethylphenyl)-2H-tetrazol-5-yl]pyridine | HCID 9965821 | — |
Reaction Steps
Following the procedure described in EXAMPLE 1 for the synthesis of 2-[2-(3-chlorophenyl)-2H-tetrazol-5-yl]pyridine, 3-trifluoromethylaniline (195 mg, 1.2 mmol) and pyridine-2-carboxaldehyde (128 mg, 1.2 mmol) were employed to obtain 2-[2-(3-trifluoromethylphenyl)-2H-tetrazol-5-yl]pyridine as an orange solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07253190B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-e512582ce1bd4384847d9c56689bded5 |
| Source note | uspto-grants-2007_08 |