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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 852328Generated: October 30, 2026

2-Pyridinecarboxaldehyde → 2-[2-(3-fluorophenyl)-2H-tetrazol-5-yl]pyridine

https://huagongshe.com/reaction/852328

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-PyridinecarboxaldehydeHCID 14273—
Reactant3-FluorodiphenylamineHCID 2774466—
Reactant2-[2-(3-chlorophenyl)-2H-tetrazol-5-yl]pyridineHCID 9921369—
Product2-[2-(3-fluorophenyl)-2H-tetrazol-5-yl]pyridineHCID 69153029—

Reaction Steps

Following the procedure described in EXAMPLE 1 for the synthesis of 2-[2-(3-chlorophenyl)-2H-tetrazol-5-yl]pyridine, 3-fluorophenylaniline (33.3 mg, 0.3 mmol) and 2-pyridinecarboxaldehyde (32.1 mg, 0.3 mmol) were employed to obtain 2-[2-(3-fluorophenyl)-2H-tetrazol-5-yl]pyridine as an orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07253190B2
Source datasetuspto-grants-2007_08
ORD IDord-a2b2f27e00d7426b97c919f9a3731bea
Source noteuspto-grants-2007_08