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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 852356Generated: October 30, 2026

Benzene, 1-(4-iodo-1-butyn-1-yl)-4-(trifluoromethyl)- → 2-Methyl-2-{2-methyl-4-[4-(4-trifluoromethyl-phenyl)-but-3-ynylsulfanyl]-phenoxy}-propionic acid ethyl ester

https://huagongshe.com/reaction/852356

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-(4-iodo-1-butyn-1-yl)-4-(trifluoromethyl)-HCID 69458210—
Reactant2-(4-Acetylsulfanyl-2-methyl-phenoxy)-2-methyl-propionic acid ethyl esterHCID 86597820—
Product2-Methyl-2-{2-methyl-4-[4-(4-trifluoromethyl-phenyl)-but-3-ynylsulfanyl]-phenoxy}-propionic acid ethyl esterHCID 69460333—

Reaction Steps

In analogy to the procedure described in example 1D], 2-(4-acetylsulfanyl-2-methyl-phenoxy)-2-methyl-propionic acid ethyl ester (example 1C]) was reacted with 1-(4-iodo-but-1-ynyl)-4-trifluoromethyl-benzene (example 2E]) to give the title compound as colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07253192B2
Source datasetuspto-grants-2007_08
ORD IDord-c2813a27cf19480a9a2be4bc121549da
Source noteuspto-grants-2007_08