4-Pentyn-1-ol → 4-Pentyn-1-ol, 5-[3-(trifluoromethoxy)phenyl]-

HRID 852361Notes

Reaction equation

HRID 852361 reaction equation
I[C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([O:8][C:9]([F:12])([F:11])[F:10])[CH:3]=1.[CH2:13]([OH:18])[CH2:14][CH2:15][C:16]#[CH:17]>>[F:10][C:9]([F:12])([F:11])[O:8][C:4]1[CH:3]=[C:2]([C:17]#[C:16][CH2:15][CH2:14][CH2:13][OH:18])[CH:7]=[CH:6][CH:5]=1

Participants

3

Reactant 2

HCID 793464-Pentyn-1-olHCID 27772931-Iodo-3-(trifluoromethoxy)benzene

Product 1

HCID 688216934-Pentyn-1-ol, 5-[3-(trifluoromethoxy)phenyl]-

Procedure

In analogy to the procedures described in example 1F], 1-iodo-3-trifluoromethoxy-benzene and pent-4-yn-1-ol gave the title compound as a red liquid.

Sources & evidence

ORD record
ord-511d39831e474d329fee61526491df2a
Source dataset
uspto-grants-2007_08
Patent number
US07253192B2

Reaction notes

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