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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 852368Generated: October 30, 2026

Benzene, 1-iodo-2-(trifluoromethyl)- → {2-Methyl-4-[3-(2-trifluoromethyl-phenyl)-prop-2-ynylsulfanyl]-phenoxy}-acetic acid tert-butyl ester

https://huagongshe.com/reaction/852368

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-iodo-2-(trifluoromethyl)-HCID 67957—
Reactant(2-Methyl-4-prop-2-ynylsulfanyl-phenoxy)-acetic acid tert-butyl esterHCID 86602538—
Product{2-Methyl-4-[3-(2-trifluoromethyl-phenyl)-prop-2-ynylsulfanyl]-phenoxy}-acetic acid tert-butyl esterHCID 69460627—

Reaction Steps

In analogy to the procedure described in example 5B], (2-methyl-4-prop-2-ynylsulfanyl-phenoxy)-acetic acid tert-butyl ester (example 5A]) and 1-iodo-2-trifluoromethyl-benzene gave the title compound as a light yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07253192B2
Source datasetuspto-grants-2007_08
ORD IDord-fd2f29cda7384315a5cf3f4ff6ccb4a6
Source noteuspto-grants-2007_08