Iodobenzene → [2-Methyl-4-(3-phenyl-prop-2-ynylsulfanyl)-phenoxy]-acetic acid tert-butyl ester

HRID 852371Notes

Reaction equation

HRID 852371 reaction equation
[C:1]([O:5][C:6](=[O:20])[CH2:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([S:15][CH2:16][C:17]#[CH:18])=[CH:11][C:10]=1[CH3:19])([CH3:4])([CH3:3])[CH3:2].I[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[C:1]([O:5][C:6](=[O:20])[CH2:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([S:15][CH2:16][C:17]#[C:18][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[CH:11][C:10]=1[CH3:19])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 11575IodobenzeneHCID 86602538(2-Methyl-4-prop-2-ynylsulfanyl-phenoxy)-acetic acid tert-butyl ester

Product 1

HCID 69458701[2-Methyl-4-(3-phenyl-prop-2-ynylsulfanyl)-phenoxy]-acetic acid tert-butyl ester

Procedure

In analogy to the procedure described in example 5B], (2-methyl-4-prop-2-ynylsulfanyl-phenoxy)-acetic acid tert-butyl ester (example 5A]) and iodo-benzene gave the title compound as a colorless oil.

Sources & evidence

ORD record
ord-ed6edcf632dc4915a26ad748a7b191fe
Source dataset
uspto-grants-2007_08
Patent number
US07253192B2

Reaction notes

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