4-Chloro-1-butyne → (4-But-3-ynylsulfanyl-2-methyl-phenoxy)-acetic acid tert-butyl ester

HRID 852373Notes

Reaction equation

HRID 852373 reaction equation
[C:1]([O:5][C:6](=[O:20])[CH2:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([S:15][C:16](=O)[CH3:17])=[CH:11][C:10]=1[CH3:19])([CH3:4])([CH3:3])[CH3:2].Cl[CH2:22][CH2:23]C#C>>[C:1]([O:5][C:6](=[O:20])[CH2:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([S:15][CH2:16][CH2:17][C:22]#[CH:23])=[CH:11][C:10]=1[CH3:19])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 401734-Chloro-1-butyneHCID 11572955(4-Acetylsulfanyl-2-methyl-phenoxy)-acetic acid tert-butyl ester

Product 1

HCID 86602539(4-But-3-ynylsulfanyl-2-methyl-phenoxy)-acetic acid tert-butyl ester

Procedure

In analogy to the procedure described in example 5A], (4-acetylsulfanyl-2-methyl-phenoxy)-acetic acid tert-butyl ester (example 4A]) and 4-chloro-but-1-yne gave the title compound as orange oil.

Sources & evidence

ORD record
ord-6f83f3ae08a54cd2a48a7cf5f1905225
Source dataset
uspto-grants-2007_08
Patent number
US07253192B2

Reaction notes

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