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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 852377Generated: October 26, 2026

1-Chloro-4-iodobenzene → 2-{4-[5-(4-Chloro-phenyl)-pent-4-ynyloxy]-2-methyl-phenoxy}-2-methyl-propionic acid ethyl ester

https://huagongshe.com/reaction/852377

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-4-iodobenzeneHCID 12510—
Reactant2-Methyl-2-(2-methyl-4-pent-4-ynyloxy-phenoxy)-propionic acid ethyl esterHCID 86602540—
Product2-{4-[5-(4-Chloro-phenyl)-pent-4-ynyloxy]-2-methyl-phenoxy}-2-methyl-propionic acid ethyl esterHCID 69458983—

Reaction Steps

In analogy to the procedure described in example 13B], 2-methyl-2-(2-methyl-4-pent-4-ynyloxy-phenoxy)-propionic acid ethyl ester (example 13A]) and 1-chloro-4-iodo-benzene gave the title compound as a yellow viscous oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07253192B2
Source datasetuspto-grants-2007_08
ORD IDord-e9d572438ecf413cb46b52a59ce3ef99
Source noteuspto-grants-2007_08