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HRID852394

反应详情

EQUATION

反应方程式

HRID 852394 的结构方程式

REACTANTS

反应物

2
结构：FC(F)(F)c1ncc(Cl)cn1
HCID33697960

5-Chloro-2-(trifluoromethyl)pyrimidine

C5H2ClF3N2

结构：C#CCCCOc1ccc(OC(C)(C)C(=O)O)c(C)c1
HCID86602542

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(OCCCC#Cc2cnc(C(F)(F)F)nc2)ccc1OC(C)(C)C(=O)O
HCID11531891

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in example 24E], 5-chloro-2-trifluoromethyl-pyrimidine (example 28B]) and 2-methyl-2-(2-methyl-4-pent-4-ynyloxy-phenoxy)-propionic acid (example 26B]), followed by flash chromatography (SiO2, CH2Cl2/MeOH 2.5 to 10%) and precipitation ether/n-pentane yielded the title compound as white powder, mp. 95-97° C., dec.

WORKUP

后处理

  1. customfollowed by flash chromatography (SiO2, CH2Cl2/MeOH 2.5 to 10%) and precipitation ether/n-pentane