1-Iodo-4-(trifluoromethoxy)benzene → HCID 69458662, compound

HRID 852418Notes

Reaction equation

HRID 852418 reaction equation
[CH2:1]([O:3][C:4](=[O:24])[C:5]([CH3:23])([O:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH2:15][C:16]2([CH2:19][C:20]#[CH:21])[CH2:18][CH2:17]2)=[CH:10][C:9]=1[CH3:22])[CH3:6])[CH3:2].I[C:26]1[CH:31]=[CH:30][C:29]([O:32][C:33]([F:36])([F:35])[F:34])=[CH:28][CH:27]=1>>[CH2:1]([O:3][C:4](=[O:24])[C:5]([CH3:23])([O:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH2:15][C:16]2([CH2:19][C:20]#[C:21][C:26]3[CH:27]=[CH:28][C:29]([O:32][C:33]([F:34])([F:35])[F:36])=[CH:30][CH:31]=3)[CH2:18][CH2:17]2)=[CH:10][C:9]=1[CH3:22])[CH3:6])[CH3:2]

Participants

3

Reactant 2

HCID 27772941-Iodo-4-(trifluoromethoxy)benzeneHCID 86602546HCID 86602546, compound

Product 1

HCID 69458662HCID 69458662, compound

Procedure

In analogy to the procedure described in example 24E), reaction of 2-methyl-2-[2-methyl-4-(1-prop-2-ynyl-cyclopropylmethoxy)-phenoxy]-propionic acid ethyl ester (example 35I]) and 1-iodo-4-trifluoromethoxybenzene gave the title compound as light yellow oil.

Sources & evidence

ORD record
ord-ab3adbd5a8474f1c9c6dc7c0b173f1d3
Source dataset
uspto-grants-2007_08
Patent number
US07253192B2

Reaction notes

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