Aluminium lithium hydride → HCID 69461118, compound

HRID 852421Notes

Reaction equation

HRID 852421 reaction equation
C([O:5][C:6]([C:8]1([CH2:11][C:12]#[C:13][Si:14]([CH3:17])([CH3:16])[CH3:15])[CH2:10][CH2:9]1)=O)(C)(C)C.[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[CH3:17][Si:14]([CH3:15])([CH3:16])[C:13]#[C:12][CH2:11][C:8]1([CH2:6][OH:5])[CH2:10][CH2:9]1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 69459163HCID 69459163, compound

Product 1

HCID 69461118HCID 69461118, compound

Procedure

In analogy to the procedure described in example 24D], reduction of the crude 1-(3-trimethylsilanyl-prop-2-ynyl)-cyclopropane carboxylic acid tert-butyl ester with LAH (1 M in THF) gave after naturally warming up to ambient temperature (during 2.75 h) the title compound as yellow oil.

Workup

  1. customgave

Sources & evidence

ORD record
ord-328da38c2e0145e3a573f0eef80a97b2
Source dataset
uspto-grants-2007_08
Patent number
US07253192B2

Reaction notes

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