Ethyl 2-(4-hydroxy-2-methylphenoxy)-2-methylpropanoate → HCID 69459774, compound

HRID 852424Notes

Reaction equation

HRID 852424 reaction equation
I[CH2:2][C:3]1([CH2:6][C:7]#[C:8][Si:9]([CH3:12])([CH3:11])[CH3:10])[CH2:5][CH2:4]1.[CH2:13]([O:15][C:16](=[O:29])[C:17]([O:20][C:21]1[CH:26]=[CH:25][C:24]([OH:27])=[CH:23][C:22]=1[CH3:28])([CH3:19])[CH3:18])[CH3:14]>>[CH2:13]([O:15][C:16](=[O:29])[C:17]([CH3:19])([O:20][C:21]1[CH:26]=[CH:25][C:24]([O:27][CH2:2][C:3]2([CH2:6][C:7]#[C:8][Si:9]([CH3:12])([CH3:11])[CH3:10])[CH2:5][CH2:4]2)=[CH:23][C:22]=1[CH3:28])[CH3:18])[CH3:14]

Participants

3

Reactant 2

HCID 16756990Ethyl 2-(4-hydroxy-2-methylphenoxy)-2-methylpropanoateHCID 69461161HCID 69461161, compound

Product 1

HCID 69459774HCID 69459774, compound

Procedure

In analogy to the procedure described in example 20A], [3-(1-iodomethyl-cyclopropyl)-prop-1-ynyl]-trimethylsilane and 2-(4-hydroxy-2-methyl-phenoxy)-2-methyl-propionic acid ethyl ester (described in WO 02/092590) gave after 18 h at room temperature the title compound as light yellow oil.

Sources & evidence

ORD record
ord-87dae930c60b4f9d839542fc3f4657db
Source dataset
uspto-grants-2007_08
Patent number
US07253192B2

Reaction notes

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