Tetrabutylammonium Fluoride → HCID 86602546, compound

Participants

Reaction Steps

A solution of 0.201 (0.50 mmol) 2-methyl-2-{2-methyl-4-[1-(3-trimethylsilanyl-prop-2-ynyl)-cyclopropylmethoxy]-phenoxy}-propionic acid ethyl ester in 5 ml THF were treated at 0° C. with 0.55 ml (1 M solution in THF, 0.55 mmol) of n-Bu4NF and stirred for 1.5 h at this temperature. The reaction mixture was then diluted with water and extracted with ether (three times). The organic layers were washed with water, dried (Na2SO4) and evaporated to give 0.152 g of the title compound as light yellow oil.

Provenance & Evidence