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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 852463Generated: October 30, 2026

Potassium Hydroxide → HCID 22499392, compound

https://huagongshe.com/reaction/852463

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium HydroxideHCID 14797—
ReactantHCID 20773936HCID 20773936—
SolventIsopropanolHCID 3776—
ProductHCID 22499392HCID 22499392107.3%

Reaction Steps

A mixture of intermediate (30) (0.0006 mol) and potassium hydroxide (0.006 mol) in isopropanol (5 ml) was stirred at room temperature overnight. The solvent was evaporated. The residue was dissolved in isopropanol/HCl 6N and converted into the hydrochloric acid salt. The precipitate was filtered off and dried, yielding 0.31 g of 4-[4-[[2-(2-furanyl)benzoyl]amino]phenyl]-α-phenyl-1-piperazineacetic acid (intermediate 31).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07253157B2
Source datasetuspto-grants-2007_08
ORD IDord-e9b118fdc698432aab6da431ed8b7052
Source noteuspto-grants-2007_08