HCID 69357218, compound → HCID 69360788, compound

HRID 852585Notes

Reaction equation

HRID 852585 reaction equation
O=S1(=O)CCCN1C1C(F)=C(C=C([N+]([O-])=O)C=1)C(OC)=O.Cl[CH2:23][CH2:24][CH2:25][CH2:26][S:27]([NH:30][C:31]1[C:32]([F:44])=[C:33]([CH:38]=[C:39]([N+:41]([O-:43])=[O:42])[CH:40]=1)[C:34]([O:36][CH3:37])=[O:35])(=[O:29])=[O:28]>>[O:28]=[S:27]1(=[O:29])[CH2:26][CH2:25][CH2:24][CH2:23][N:30]1[C:31]1[C:32]([F:44])=[C:33]([CH:38]=[C:39]([N+:41]([O-:43])=[O:42])[CH:40]=1)[C:34]([O:36][CH3:37])=[O:35]

Participants

3

Reactant 2

HCID 69357218HCID 69357218, compoundHCID 69359224HCID 69359224, compound

Product 1

HCID 69360788HCID 69360788, compound

Procedure

Methyl 3-(1,1-dioxidotetrahydro-2H-1,2-thiazin-2-yl)-2-fluoro-5-nitrobenzoate (D148) was prepared in an analogous manner to the process for methyl 3-(1,1-dioxido-2-isothiazolidinyl)-2-fluoro-5-nitrobenzoate (D147) from methyl 3-{[(4-chlorobutyl)sulfonyl]amino}-2-fluoro-5-nitrobenzoate (D146). [M+H+ NH3]+=350.1, RT=2.79 min.

Sources & evidence

ORD record
ord-f501426526354885948ab56524505615
Source dataset
uspto-grants-2007_08
Patent number
US07253198B2

Reaction notes

Loading…