HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxybenzaldehyde → Methyl 2-fluoro-5-({[4-(methyloxy)phenyl]methyl}amino)-3-(2-oxo-1-pyrrolidinyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxybenzaldehyde | HCID 31244 | — |
| Reactant | Methyl 5-amino-2-fluoro-3-(2-oxo-1-pyrrolidinyl)benzoate | HCID 69357536 | — |
| Product | Methyl 2-fluoro-5-({[4-(methyloxy)phenyl]methyl}amino)-3-(2-oxo-1-pyrrolidinyl)benzoate | HCID 69361588 | — |
Reaction Steps
Methyl 2-fluoro-5-({[4-(methyloxy)phenyl]methyl}amino)-3-(2-oxo-1-pyrrolidinyl)benzoate (D154) was prepared from methyl 5-amino-2-fluoro-3-(2-oxo-1-pyrrolidinyl)benzoate (D150) in an analogous manner to the process described for Ester 35 (B35) using 4-(methyloxy)benzaldehyde instead of propionaldehyde. [M+H]+=373.4, RT=2.85 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07253198B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-03584a8fa5d243ed8a6cf1267fb2e367 |
| Source note | uspto-grants-2007_08 |