Ethanol → HCID 178518179, compound

Participants

Reaction Steps

1-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-yl)thiourea (887 mg, 5.25 mmol), 3-bromo-dihydrofuran-2(3 H)-one (1.65 g, 5 mmol), EtOH (10 mL) and DIEA (5.0 mL) were placed in a microwave reaction vessel. The mixture was placed in a microwave synthesizer and was irradiated at 150° C. for 30 min. The resulting mixture was poured into water and extracted with EtOAc and dried over MgSO4. After being filtered and concentrated in vacuo, the title compound was obtained a brown solid. MS (ES+): 255 (M+H)+.

Provenance & Evidence