反应详情

A solution of the oximes 100 (2.7 g 12.2 mmol) in ethanol (40 mL) was hydrogenated over 10% Pd—C at 40 psi and 50° C. for 3 days. The catalyst was filtered off and the solvent was evaporated. The residue was partitioned between ether and 0.1 M HCl and the aqueous layer was lyophilized giving 101 as a white powder (130 mg, 5%).

1. filtrationThe catalyst was filtered off
2. customthe solvent was evaporated
3. customThe residue was partitioned between ether and 0.1 M HCl