HuagongsheHuagongshe Chemistry Print Report · For research reference only
F0327-0028 → 2-Amino-6-methoxybenzothiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | F0327-0028 | HCID 324531 | — |
| Reactant | Methyl 3-(4-formylphenyl)-2-propenoate | HCID 53401287 | — |
| Product | 2-Amino-6-methoxybenzothiazole | HCID 15630 | 93% |
Reaction Steps
The title compound 162 was obtained following the procedure described in J. Med. Chem., 1979, 22 (1), 28-32, starting from 2-amino-6-methoxybenzothiazole (93% yield). 1H NMR: (DMSO-d6) δ (ppm): 9.63 (bs, 1H), 7.91 (d, J=8.4 Hz, 2H), 7.65 (d, J=8.0 Hz, 2H), 7.55-7.51 (m, 2H), 6.98 (d, J=8.8 Hz, 1H), 4.28 (q, J=6.8 Hz, 2H), 3.79 (s, 3H), 1.32 (t, J=7.2 Hz, 3H). m/z: 372.3 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07253204B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-3a0f407bb7b94167bf32fdec29863372 |
| Source note | uspto-grants-2007_08 |