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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 852954Generated: October 25, 2026

Acetylpyrazine → N-(2-Aminophenyl)-4-((4-(2-methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamide

https://huagongshe.com/reaction/852954

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetylpyrazineHCID 30914—
Reactant1-{2-Methylimidazo[1,2-a]pyridin-3-yl}ethan-1-oneHCID 2735255—
ReactantN-(2-aminophenyl)-4-((4-(pyrazin-2-yl)pyrimidin-2-ylamino)methyl)benzamideHCID 44570891—
ProductN-(2-Aminophenyl)-4-((4-(2-methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-ylamino)methyl)benzamideHCID 58930542—

Reaction Steps

Title compound was obtained according to the scheme 6 similarly to the compound 26a (Example 29) using instead of 1-pyrazin-2-yl-ethanone as the starting material the ketone 333 (Table 11). Characterization of the title compound is provided in the Table 12.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07253204B2
Source datasetuspto-grants-2007_08
ORD IDord-784bdba57de24c94ade49cbe0dc3d4bc
Source noteuspto-grants-2007_08