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HRID852955

反应详情

EQUATION

反应方程式

HRID 852955 的结构方程式

REACTANTS

反应物

3
结构：CC(=O)c1cnccn1
HCID30914

Acetylpyrazine

C6H6N2O

结构：CN(C)/C=C/C(=O)c1cnccn1
HCID5825354

未命名化合物

结构：CC(=O)c1sc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nc1C
HCID58930550

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)sc1C(=O)/C=C/N(C)C
HCID58930666

未命名化合物

收率 16%

PROCEDURE

实验过程

Following the procedure described for the synthesis of enamino ketone 23a (scheme 6) but substituting 1-(pyrazin-2-yl)-ethanone for the ketone 336, title compound was obtained in 16% yield. 1H NMR (DMSO-d6) δ (ppm): 7.65 (d, J=12.1 Hz, 1H), 5.34 (d, J=12.1 Hz, 1H), 3.14 (s, 3H), 2.87 (s, 3H), 2.50 (s, 3H), 1.51 (s, 18H). MS (m/z): 411.52 (calc) 412.3 (MH+) (found).