HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 58615384, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | CID 76231 | HCID 76231 | — |
| Reactant | HCID 58615400 | HCID 58615400 | — |
| Reactant | HCID 178418416 | HCID 178418416 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Product | HCID 58615384 | HCID 58615384 | — |
Reaction Steps
The similar procedure as described in Example 10b was used, starting from 4-(6-iodo-quinolin-4-yloxy)-piperidine-1-carboxylic acid tert-butyl ester (example 48a), diphenylpropyl phsophine, palladium acetate, triethyl amine, and trihexylsilane in anhydrous DMF (25 ml) was charged with carbon monoxide at 75 psi to give 4-(6-formyl-quinolin-4-yloxy)-piperidine-1-carboxylic acid tert-butyl ester. LC-MS m/e 357 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07253285B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-edb31175ce374aa7af51f8ef93f64c43 |
| Source note | uspto-grants-2007_08 |