(s)-Tert-butyl 5-methyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide → HCID 68888919, compound
Reaction equation
[CH2:1]([O:3][C:4]([C:6]1[NH:7][C:8]2[C:16]([CH:17]=1)=[CH:15][CH:14]=[C:13]1[C:9]=2[CH2:10][CH2:11][CH2:12]1)=[O:5])[CH3:2].[C:18]([O:22][C:23]([N:25]1[CH2:29][C@H:28]([CH3:30])OS1(=O)=O)=[O:24])([CH3:21])([CH3:20])[CH3:19]>>[CH2:1]([O:3][C:4]([C:6]1[N:7]([C@H:28]([CH3:30])[CH2:29][NH:25][C:23]([O:22][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:24])[C:8]2[C:16]([CH:17]=1)=[CH:15][CH:14]=[C:13]1[C:9]=2[CH2:10][CH2:11][CH2:12]1)=[O:5])[CH3:2]Participants
3
Procedure
The title compound was prepared in accordance with the general method of example 12b) from b) 1,6,7,8-tetrahydro-1-aza-as-indacene-2-carboxylic acid ethyl ester and (S)-5-methyl-2,2-dioxo-[1,2,3]oxathiazolidine-3-carboxylic acid tert-butyl ester.
Sources & evidence
- ORD record
- ord-a0793e6f41b5456f8f5bb35c5990478c
- Source dataset
- uspto-grants-2007_08
- Patent number
- US07253281B2
Reaction notes
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