HuagongsheHuagongshe Chemistry Print Report · For research reference only
Monobenzone → Methyl 2-[p-(benzyloxy)phenoxy]propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Monobenzone | HCID 7638 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | Methyl 2-bromopropionate | HCID 95576 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | Methyl 2-[p-(benzyloxy)phenoxy]propionate | HCID 13093988 | — |
Reaction Steps
In analogy to the procedure described in Example 1b), the alkylation of 4-benzyloxy-phenol [Example 2a)] with methyl (RS)-2-bromopropionate in acetone using cesium carbonate as the base yielded the (RS)-2-(4-Benzyloxy-phenoxy)-propionic acid methyl ester as light yellow oil; MS: m/e=304 (M+NH4)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07253318B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-fc1bbd4eea9c4f278f67d31592e7bb8f |
| Source note | uspto-grants-2007_08 |