HRID853199

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(=O)c1ccc2c(c1)C(C)(C)C=C2c1ccc(C)cc1

HCID57423816

未命名化合物

2 次

结构：Cc1ccc(C2=CCC(C)(C)c3cc(C(=O)C=Cc4ccc(C(=O)OCC[Si](C)(C)C)cc4)ccc32)cc1

HCID68832141

未命名化合物

2 次

PRODUCTS

生成物

结构：Cc1ccc(C2=CC(C)(C)c3cc(C(=O)C=Cc4ccc(C(=O)OCC[Si](C)(C)C)cc4)ccc32)cc1

HCID68829173

未命名化合物

收率 25%

PROCEDURE

实验过程

Following a procedure similar to that for the preparation of 2-trimethylsilanyl-ethyl 4-[3-(8,8-dimethyl-5-p-tolyl-7,8-dihydro-naphthalen-2-yl)-3-oxo-propenyl]-benzoate (Compound 6) while using 1-(3,3-dimethyl-1-p-tolyl-3H-inden-5-yl)-ethanone (Compound 14, 200 mg, 0.72 mmol) as the starting material yielded the title compound (93 mg, 25% yield) as a yellow solid:

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-776a443f85904966ae6048ded2c95e65
来源数据集: uspto-grants-2007_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07253319B2
来源说明: uspto-grants-2007_08

反应 SMILES

CC1(C)C2[CH:10]=[C:9]([C:12](=[O:30])[CH:13]=[CH:14][C:15]3[CH:29]=[CH:28][C:18]([C:19]([O:21][CH2:22][CH2:23][Si:24]([CH3:27])([CH3:26])[CH3:25])=[O:20])=[CH:17][CH:16]=3)[CH:8]=[CH:7]C=2C(C2C=CC(C)=CC=2)=CC1.[CH3:39][C:40]1([CH3:59])[C:48]2[C:43](=CC=C(C(=O)C)C=2)[C:42]([C:52]2[CH:57]=[CH:56][C:55]([CH3:58])=[CH:54][CH:53]=2)=[CH:41]1>>[CH3:39][C:40]1([CH3:59])[C:48]2[C:43](=[CH:7][CH:8]=[C:9]([C:12](=[O:30])[CH:13]=[CH:14][C:15]3[CH:16]=[CH:17][C:18]([C:19]([O:21][CH2:22][CH2:23][Si:24]([CH3:25])([CH3:26])[CH3:27])=[O:20])=[CH:28][CH:29]=3)[CH:10]=2)[C:42]([C:52]2[CH:53]=[CH:54][C:55]([CH3:58])=[CH:56][CH:57]=2)=[CH:41]1