3-(Methylthio)propylamine → HCID 21949116, compound

HRID 853406Notes

Reaction equation

HRID 853406 reaction equation
[CH3:1][S:2][CH2:3][CH2:4][CH2:5][NH2:6].[CH3:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[C:13]([O:16]CC)(=[O:15])C>>[CH3:1][S:2][CH2:3][CH2:4][CH2:5][NH:6][C:13](=[O:15])[O:16][C:9]1[CH:8]=[CH:7][CH:12]=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 777433-(Methylthio)propylamineHCID 21226206Ethyl acetate hexane

Product 1

HCID 21949116HCID 21949116, compoundYield 93.08%

Procedure

3-Methylthiopropylamine (5.5 ml, 50 mmol) was used for reaction in the same manner as Production Example 310-1, and purification was performed by silica gel column chromatography (hexane/ethyl acetate system) to obtain the title compound (10.486 g, 46.54 mmol, 93.08%) as a yellow oil.

Sources & evidence

ORD record
ord-169907a821d948678d0444e6dbb6c782
Source dataset
uspto-grants-2007_08
Patent number
US07253286B2

Reaction notes

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