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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 853497Generated: October 30, 2026

4-(4-Nitrophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl ester → 4-(4-Aminophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/853497

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Nitrophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl esterHCID 58931497—
CatalystIronHCID 23925—
Product4-(4-Aminophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl esterHCID 5893146286.9%

Reaction Steps

4-(4-Nitrophenoxy)-furo[2.3-b]pyridine-2-carboxylic acid methyl ester (70 mg) was subjected to iron reduction by the same method as in Production Example 10 to obtain the title compound (55 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07253286B2
Source datasetuspto-grants-2007_08
ORD IDord-4d23a21143af4280aa61a0bbf85790e4
Source noteuspto-grants-2007_08