反应详情

From 9 (488 mg, 2 mmol) and 2-chlorobenzylzinc chloride (0.5 Min THF, 10 mL, 5 mmol) by the same methods as 10a; white powder (272 mg, 62%), mp 79-80° C.; 1H NMR (CDCl3) δ 3.96 (s, 2H, CH2), 4.79 (br s, 2H, NH2), 6.69 (d, J=8.8 Hz, 1H, H-3), 7.12-7.19 (m, 5H, aromatic protons), 7.20 (s, 1H, H-6).