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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 854243Generated: October 25, 2026

2,2-Dimethyl-3-(piperidin-1-yl)propan-1-ol → [6-(2,2-Dimethyl-3-piperidin-1-yl-propoxy)-naphthalen-2-yl]-(4-methyl-piperidin-1-yl)-methanone

https://huagongshe.com/reaction/854243

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-Dimethyl-3-(piperidin-1-yl)propan-1-olHCID 296014—
Reactant(6-Hydroxy-naphthalen-2-yl)-(4-methyl-piperidin-1-yl)-methanoneHCID 58933892—
Product[6-(2,2-Dimethyl-3-piperidin-1-yl-propoxy)-naphthalen-2-yl]-(4-methyl-piperidin-1-yl)-methanoneHCID 69062749—

Reaction Steps

The title compound was synthesised from (6-hydroxy-naphthalen-2-yl)-(4-methyl-piperidin-1-yl)-methanone (intermediate B) and 2,2-dimethyl-3-piperidin-1-yl-propan-1-ol (commercially available) according to the procedure described for the synthesis of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07259158B2
Source datasetuspto-grants-2007_08
ORD IDord-5b8f75d9397d44d9802d832b0a2c9862
Source noteuspto-grants-2007_08