1-Naphthalenesulfonyl chloride → HCID 86760528, compound

HRID 854260Notes

Reaction equation

HRID 854260 reaction equation
[C:1]([O:5][C:6](=[O:22])[C@@H:7]([NH2:21])[CH2:8][S:9][S:10][CH2:11][C@H:12]([NH2:20])[C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])([CH3:4])([CH3:3])[CH3:2].[C:23]1([S:33](Cl)(=[O:35])=[O:34])[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[CH:26]=[CH:25][CH:24]=1>>[C:16]([O:15][C:13](=[O:14])[C@@H:12]([NH:20][S:33]([C:23]1[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[CH:26]=[CH:25][CH:24]=1)(=[O:35])=[O:34])[CH2:11][S:10][S:9][CH2:8][C@H:7]([NH:21][S:33]([C:23]1[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[CH:26]=[CH:25][CH:24]=1)(=[O:35])=[O:34])[C:6]([O:5][C:1]([CH3:4])([CH3:2])[CH3:3])=[O:22])([CH3:19])([CH3:18])[CH3:17]

Participants

3

Reactant 2

HCID 665601-Naphthalenesulfonyl chlorideHCID 6993299HCID 6993299, compound

Product 1

HCID 86760528HCID 86760528, compound

Procedure

Preparation in analogy to example 6a from 1 g (2.35 mmol) of (R)-cystine-bis-tert-butylester and 1.32 g (5.8 mmol) of 1-naphthalenesulfonic acid chloride. Yield: 1.78 g (oily crystals).

Sources & evidence

ORD record
ord-790f3d07405b4a2aa9e3a93dbf200bc2
Source dataset
uspto-grants-2007_08
Patent number
US07259159B2

Reaction notes

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