Benzenesulfonyl chloride → HCID 86760530, compound

HRID 854262Notes

Reaction equation

[C:1]([O:5][C:6](=[O:22])[C@@H:7]([NH2:21])[CH2:8][S:9][S:10][CH2:11][C@H:12]([NH2:20])[C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])([CH3:4])([CH3:3])[CH3:2].[C:23]1([S:29](Cl)(=[O:31])=[O:30])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[C:16]([O:15][C:13](=[O:14])[C@@H:12]([N:20]([S:29]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)(=[O:31])=[O:30])[S:29]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)(=[O:31])=[O:30])[CH2:11][S:10][S:9][CH2:8][C@H:7]([NH2:21])[C:6]([O:5][C:1]([CH3:4])([CH3:2])[CH3:3])=[O:22])([CH3:19])([CH3:18])[CH3:17]

Participants

Reactant 2

HCID 7369Benzenesulfonyl chloride

HCID 6993299HCID 6993299, compound

Product 1

HCID 86760530HCID 86760530, compound

Procedure

Preparation in analogy to example 6a from 1 g (2.35 mmol) of (R)-cystine-bis-tert-butylester and 0.83 g (4.7 mmol) benzenesulfonic acid chloride. Yield: 1.5 g.

Sources & evidence

ORD record: ord-0aca873e8c0c42e5ac0d422fb4362339
Source dataset: uspto-grants-2007_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07259159B2

Reaction notes

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