HCID 29031334、化合物 → 4-Hydroxy-N-piperidin-3-ylmethyl-benzamide

HRID 854317ノート

反応式

HRID 854317 の反応式
[OH:1][C:2]1[CH:17]=[CH:16][C:5]([C:6]([NH:8][CH2:9][C:10]2[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=2)=[O:7])=[CH:4][CH:3]=1>C(O)(=O)C.[Pt]=O>[OH:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([NH:8][CH2:9][CH:10]2[CH2:15][CH2:14][CH2:13][NH:12][CH2:11]2)=[O:7])=[CH:16][CH:17]=1

参加物

4

反応物 1

HCID 29031334HCID 29031334、化合物

生成物 1

HCID 201197334-Hydroxy-N-piperidin-3-ylmethyl-benzamide

試薬・触媒・溶媒 2

HCID 82844Platinum oxide (PtO)触媒HCID 176Acetic Acid溶媒

実験手順

To a solution of 4-hydroxy-N-pyridin-3-ylmethyl-benzamide (2.0 g, 0.0088 mol) in acetic acid (135 mL) was added platinum oxide (200 mg) and the mixture stirred under hydrogen for 3 h. The reaction was filtered and concentrated in vacuo to give an oil.

後処理

  1. filtrationThe reaction was filtered
  2. concentrationconcentrated in vacuo
  3. customto give an oil

出典と根拠

ORDレコード
ord-c15a11b851f54178add2bf575d380ac6
出典データセット
uspto-grants-2007_08
特許番号
US07259157B2

反応ノート

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