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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 854328Generated: October 25, 2026

4-Aminomethyl-1-N-Cbz-piperidine → Benzyl 4-[({[2-(methylsulfonyl)pyrimidin-4-yl]carbonyl}amino)methyl]piperidine-1-carboxylate

https://huagongshe.com/reaction/854328

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Aminomethyl-1-N-Cbz-piperidineHCID 21955499—
Reactant2-Methanesulfonylpyrimidine-4-carboxylic acidHCID 21992201—
ProductBenzyl 4-[({[2-(methylsulfonyl)pyrimidin-4-yl]carbonyl}amino)methyl]piperidine-1-carboxylateHCID 58933684—

Reaction Steps

2-(Methylsulfonyl)pyrimidine-4-carboxylic acid was coupled to benzyl 4-(aminomethyl)piperidine-1-carboxylate according to the procedure for EXAMPLE 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07259157B2
Source datasetuspto-grants-2007_08
ORD IDord-e7f9016edb334107b5e41fb60dbd786d
Source noteuspto-grants-2007_08