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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 854333Generated: November 1, 2026

4-Hydroxybenzoic Acid → Benzyl 4-fluoro-4-{[(4-hydroxybenzoyl)amino]methyl}piperidine-1-carboxylate

https://huagongshe.com/reaction/854333

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Hydroxybenzoic AcidHCID 135—
ReactantBenzyl 4-(aminomethyl)-4-fluoropiperidine-1-carboxylateHCID 22135645—
ProductBenzyl 4-fluoro-4-{[(4-hydroxybenzoyl)amino]methyl}piperidine-1-carboxylateHCID 58933555—

Reaction Steps

4-Hydroxy benzoic acid was coupled to benzyl 4-(aminomethyl)-4-fluoropiperidine-1-carboxylate according to the procedure for EXAMPLE 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07259157B2
Source datasetuspto-grants-2007_08
ORD IDord-f6a919f067b54d7d9af558bb4b026542
Source noteuspto-grants-2007_08