HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetaldehyde → 2-[N-(Methylmethylene)amino]-4methylpentanoic acid, tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetaldehyde | HCID 177 | — |
| Reactant | Sodium Sulfate | HCID 24436 | — |
| Reactant | tert-butyl (2S)-2-amino-4-methylpentanoate | HCID 7022311 | — |
| Product | 2-[N-(Methylmethylene)amino]-4methylpentanoic acid, tert-butyl ester | HCID 58934007 | — |
Reaction Steps
A solution of leucine tert-butyl ester (2.0 g, 8.9 mmol) and acetaldehyde (999 ul, 17.9 mmol) was stirred at room temperature for 5 minutes. Anhydrous sodium sulphate was added and the mixture stirred at room temperature for 18 hours. The solid was removed by filtration and the solvent evaporated in vacuo to afford the title compound as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07259163B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-948466db67134022aee4612d43eca131 |
| Source note | uspto-grants-2007_08 |