HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-chloro-N-[(1R)-1-phenylethyl]pyrazin-2-amine → N-[(1R)-1-Phenylethyl]-6-(4-phenyl-1H-imidazol-1-yl)pyrazin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-chloro-N-[(1R)-1-phenylethyl]pyrazin-2-amine | HCID 58717082 | — |
| Reactant | HCID 178418822 | HCID 178418822 | — |
| Product | N-[(1R)-1-Phenylethyl]-6-(4-phenyl-1H-imidazol-1-yl)pyrazin-2-amine | HCID 10315266 | 67% |
Reaction Steps
In a procedure analogous to example 2, reaction of 6-chloro-N-[(1R)-1-phenylethyl]pyrazin-2-amine (180 mg, 0.77 mmol) and 4-phenylimidazole (122 mg, 0.85 mmol) furnished the product (176 mg, 67%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07259179B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-91822874765642b682f6f9fc59917d42 |
| Source note | uspto-grants-2007_08 |