Benzylamine → HCID 178522795, compound

HRID 854461Notes

Reaction equation

HRID 854461 reaction equation
[N:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[NH:3][CH:2]=1.[CH2:13]([NH2:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH2:13]([NH:20][C:10]([C:8]1[CH:7]=[CH:6][C:5]2[NH:1][CH:2]=[N:3][C:4]=2[CH:9]=1)=[O:12])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 4594565-Benzimidazolecarboxylic acid

Product 1

HCID 178522795HCID 178522795, compoundYield 66%

Procedure

In a procedure analogous to example 20, reaction of benzimidazole-5-carboxylic acid (400 mg, 2.50 mmol) and benzylamine furnished the product (410 mg, 66%).

Sources & evidence

ORD record
ord-c749435c386543e08ee13cce9b2b6b96
Source dataset
uspto-grants-2007_08
Patent number
US07259179B2

Reaction notes

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