HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrazinecarbonyl chloride → HCID 10048651, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrazinecarbonyl chloride | HCID 88279 | — |
| Reactant | HCID 10314573 | HCID 10314573 | — |
| Product | HCID 10048651 | HCID 10048651 | 55% |
Reaction Steps
In a procedure analogous to example 32, reaction of 1-(6-{[(1S)-1-phenylethyl]amino}pyrazin-2-yl)-1H-benzimidazol-5-amine (33 mg, 0.10 mmol) and pyrazine-2-carbonyl chloride (0.11 mmol) (prepared by reacting pyrazine-2-carboxylic acid with oxalyl chloride in dicloromethane at room temperature) furnished the product (24 mg, 55%) after chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07259179B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-aa93b107aa5d4eb4b446347d2b5d8c41 |
| Source note | uspto-grants-2007_08 |