3-Methoxybenzaldehyde → HCID 57434510, compound

HRID 854621Notes

Reaction equation

HRID 854621 reaction equation
[I:1][CH2:2][C:3]1[N:4]=[C:5]([C:14]2[CH:19]=[CH:18][C:17](C)=[CH:16][CH:15]=2)[O:6][C:7]=1[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.C1([C:27](=[O:32])C(=NO)C)CCCCC1.C(=O)C1C=CC=C(OC)C=1>>[I:1][CH2:2][C:3]1[N:4]=[C:5]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([O:32][CH3:27])[CH:15]=2)[O:6][C:7]=1[CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1

Participants

4

Reactant 3

HCID 115693-MethoxybenzaldehydeHCID 6786725HCID 6786725, compoundHCID 574345044-Iodomethyl-5-phenyl-2-p-tolyloxazole

Product 1

HCID 57434510HCID 57434510, compound

Procedure

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, 1-cyclohexyl-1,2-propanedione-2-oxime and m-anis-aldehyde gave 4-iodomethyl-5-cyclohexyl-2-(3-methoxyphenyl)oxazole.

Sources & evidence

ORD record
ord-52fc96ee27ca435b9a60a5792eadcb29
Source dataset
uspto-grants-2007_08
Patent number
US07259177B2

Reaction notes

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