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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 854626Generated: October 26, 2026

4-Fluorobenzaldehyde → 2-(4-Fluorophenyl)-4-iodomethyl-5-methyloxazole

https://huagongshe.com/reaction/854626

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorobenzaldehydeHCID 68023—
Reactant2,3-Butanedione monoximeHCID 6409633—
Reactant4-Iodomethyl-5-phenyl-2-p-tolyloxazoleHCID 57434504—
Product2-(4-Fluorophenyl)-4-iodomethyl-5-methyloxazoleHCID 22493654—

Reaction Steps

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, diacetylmonoxime and 4-fluorobenzaldehyde gave 2-(4-fluorophenyl)-4-iodomethyl-5-methyloxazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07259177B2
Source datasetuspto-grants-2007_08
ORD IDord-a5b83212370646278f2c7e2e7e2fd32e
Source noteuspto-grants-2007_08