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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 854627Generated: October 25, 2026

4-Methoxybenzaldehyde → 2-(4-Methoxyphenyl)-4-iodomethyl-5-methyloxazole

https://huagongshe.com/reaction/854627

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzaldehydeHCID 31244—
Reactant2,3-Butanedione monoximeHCID 6409633—
Reactant4-Iodomethyl-5-phenyl-2-p-tolyloxazoleHCID 57434504—
Product2-(4-Methoxyphenyl)-4-iodomethyl-5-methyloxazoleHCID 22493659—

Reaction Steps

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, diacetylmonoxime and 4-methoxybenzaldehyde gave 4-iodomethyl-2-(4-methoxyphenyl)-5-methyloxazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07259177B2
Source datasetuspto-grants-2007_08
ORD IDord-eaa210ef041f47d5b091ec5fd3b282b4
Source noteuspto-grants-2007_08