Cuminaldehyde → HCID 57434529, compound

HRID 854637Notes

Reaction equation

HRID 854637 reaction equation
[I:1][CH2:2][C:3]1[N:4]=C(C2C=CC(C)=CC=2)O[C:7]=1[C:8]1C=CC=C[CH:9]=1.CC(=NO)C(=O)CC.[CH:29]([C:32]1[CH:39]=[CH:38][C:35]([CH:36]=[O:37])=[CH:34][CH:33]=1)([CH3:31])[CH3:30]>>[CH2:8]([C:7]1[O:37][C:36]([C:35]2[CH:34]=[CH:33][C:32]([CH:29]([CH3:31])[CH3:30])=[CH:39][CH:38]=2)=[N:4][C:3]=1[CH2:2][I:1])[CH3:9]

Participants

4

Reactant 3

HCID 326CuminaldehydeHCID 67974532,3-Pentanedione, 2-oximeHCID 574345044-Iodomethyl-5-phenyl-2-p-tolyloxazole

Product 1

HCID 57434529HCID 57434529, compound

Procedure

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, pentane-2,3-dione-2-oxime and 4-isopropylbenzaldehyde gave 5-ethyl-4-iodomethyl-2-(4-isopropylphenyl)oxazole.

Sources & evidence

ORD record
ord-4126c117c75a4c309bd4ab13ee170a2b
Source dataset
uspto-grants-2007_08
Patent number
US07259177B2

Reaction notes

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