Veratraldehyde → HCID 22493639, compound

HRID 854638Notes

Reaction equation

HRID 854638 reaction equation
[I:1][CH2:2][C:3]1[N:4]=C(C2C=CC(C)=CC=2)O[C:7]=1[C:8]1C=CC=CC=1.C/C(/C(C)=O)=N\O.[CH3:28][O:29][C:30]1[CH:31]=[C:32]([CH:35]=[CH:36][C:37]=1[O:38][CH3:39])[CH:33]=[O:34]>>[I:1][CH2:2][C:3]1[N:4]=[C:33]([C:32]2[CH:35]=[CH:36][C:37]([O:38][CH3:39])=[C:30]([O:29][CH3:28])[CH:31]=2)[O:34][C:7]=1[CH3:8]

Participants

4

Reactant 3

HCID 8419VeratraldehydeHCID 64096332,3-Butanedione monoximeHCID 574345044-Iodomethyl-5-phenyl-2-p-tolyloxazole

Product 1

HCID 22493639HCID 22493639, compound

Procedure

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, diacetylmonoxime and 3,4-dimethoxybenzaldehyde gave 4-iodomethyl-5-methyl-2-(3,4-dimethoxyphenyl)oxazole.

Sources & evidence

ORD record
ord-20cecb9dee68455883f743a30e0e37d9
Source dataset
uspto-grants-2007_08
Patent number
US07259177B2

Reaction notes

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