HCID 69243891, compound → HCID 69242949, compound

Participants

Reaction Steps

20 mg of impure tert-butyl 1-[cis-3-(5-methyl-2-p-tolyloxazol-4-ylmethoxy)-cyclohexylmethoxy]cyclopentanecarboxylate is stirred in 1 ml of trifluoroacetic acid at room temperature overnight. The solution is concentrated completely and the residue is chromatographed on silica gel (heptane/ethyl acetate 10/1->1/1->methyl tert-butyl ether), giving 7.5 mg of 1-[cis-3-(5-methyl-2-p-tolyloxazol-4-ylmethoxy)cyclohexylmethoxy]cyclo-pentanecarboxylic acid. C25H33NO5 (427.55); LCMS 428.2 (MH+).

Provenance & Evidence