HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenethylamine, (+)- → HCID 86599464, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenethylamine, (+)- | HCID 643189 | — |
| Reactant | HCID 11649854 | HCID 11649854 | — |
| Catalyst | Isopropanol | HCID 3776 | — |
| Solvent | Heptane | HCID 8900 | — |
| Product | HCID 86599464 | HCID 86599464 | — |
Reaction Steps
(S)-8-ethyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid prepared as in Example 21k (17.8 mg, 0.0500 mmole) and (1R)-1-phenylethanamine (12.7 uL, 0.0500 mmole) were added to a few drops of isopropanol. Heptane (0.30 mL) was then added and the solvent was allowed to slowly evaporate from the loosely capped vial. Crystals had formed in the solution after standing at room temperature for 1 day. X-ray crystal structure analysis confirmed the title compound to be the (S)-enantiomer.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07259266B2 |
| Source dataset | uspto-grants-2007_08 |
| ORD ID | ord-4e749c5c0dd74ba899a2e5c03131f270 |
| Source note | uspto-grants-2007_08 |